SLE,cold anitibody mediated haemolysis with Pseudohyperkalaemia
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology that can potentially affect any organ system of the body. The most common hematologic manifestations of SLE include anemia, leukopenia, thrombocytopenia, lymphadenopathy, and/or splenomegaly. Anemia occurs in around 50% of patients with SLE and the most common type of anemia is that of chronic disease. Autoimmune hemolytic anemia (AIHA) has been reported in up to 10 percent of SLE patients1-3. Autoantibodies to RBCs in SLE may be warm- or cold-reactive; however, warm autoimmune hemolysis is much more common. Only few cases of cold-antobody mediated hemolysis are reported in published literature till date4, 5, 11.
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References
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